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Monoclonal Antibody ICSM 35

Product No. 0130-03501  100µg               monoclonal anti-PrP ICSM 35

Product No. 0130-03510  1mg                  monoclonal anti-PrP ICSM 35

 

Product description

Monoclonal anti- prion protein (PrP); purified mouse immunoglobulin

The antibody isotype is IgG2bκ

Concentration

1mg/ml in 0.1M Tris/Glycine, pH 7.0, >95% pure.  The antibody is sterile filtered and contains 10mM sodium azide as preservative.

Note: Purified antibodies can be supplied without sodium azide preservative on request at the same price. When placing your order please make sure to inform us of your specific request by filling in the comments and special instructions box (for online orders) or email us at sales@d-gen.co.uk

Specificity

ICSM 35 specifically reacts with human PrPC and PrPSc in both native and denatured conformations. The antibody also reacts with sheep, mouse, hamster and bovine PrPC and PrPSc (unpublished data). The epitope is defined within the sequence 93-102 of human PrP.

Storage and Stability

This product may be stored at 0-5°C for continuous or daily use. For long term storage the antibody can be frozen in aliquots at -20°C.  Repeated freeze-thawing should be avoided.

Applications

ICSM 35 can be used for detection of PrP by immunoprecipitation, western blotting, FACS and immunohistochemistry. (WB >1mg/ml, IP & FACS 10mg/ml, the antibody has not been titrated to give a minimum working concentration)

Research Use Only

This product is for Research Use Only and must not be used for diagnostic, therapeutic or manufacturing purposes.

Health, Safety and Waste

All users of this product must ensure that:

(i)   this product's specification is safe for their intended use

(ii)  the product is handled in a safe manner using good laboratory practice and in accordance with any relevant local or national regulations pertaining to the use of such products; and

(iii) any waste originating from the product or its use is disposed of in accordance with any relevant local or national regulations.

 

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ICSM3

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ICSM10

ICSM15

ICSM18

ICSM35

 

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